Greetings and welcome new and returning Icahn School of Medicine Students! The Levy Library team is excited to be a part of your academic journey and we look forward to working with each of you in achieving your academic and research goals.
We wanted to dedicate a blog post to our library resources and services so if you are new here, you can read about what your library has to offer. If you are returning student we also wanted to share some changes to our services and visitation policies since we have adjusted our operations to endure that the health and safety of our patrons remains top priority! So take a few minutes to learn a bit more about the Levy Library and what we have to offer you:
Ask a Librarian - Connect with a member of our library team via chat, phone, or email. You can also browse the available FAQs or submit your own. Librarians are available virtually Monday-Friday 9:00am-5:00pm.
Education & Research Services - Our ERS team offers research consultations, systematic review support, and educational sessions. Check out the calendar to reserve your spot for Introduction to Endnote or one of the many Drop-In Mini Sessions being offered this Fall.
Writing Support Service - Improve your writing skills by scheduling a 1:1 consultation with an experienced science writer and editor. Consultations are virtual and complimentary!
Keeping You Safe - Our top priority is maintaining the safety of every person that enters The Levy Library. For the protection of our patrons and staff, all visitors are required to wear a mask, maintain social distancing, and practice proper hand hygiene. Study spaces and common areas are cleaned frequently throughout the day.
What’s Available - The library is currently in Phase 1 of reopening. Tables and carrels are available for single-person use with advanced reservation. Public computers and computer labs are closed at this time. The current hours of operation are as follows:
- Monday – Friday: 9:00am- 4:00pm
- Saturday and Sunday: CLOSED
Printing Services – While the printers in the Levy Library are closed, you still have access to the printers located in the Aron Hall residence lounge and ANBG 13th floor student lounge. A print account has been created for you and has been filled with $50 just in case you need to print something out. You can learn more about printing and get access to your My Print Center account by visiting libguides.mssm.edu/technology/howtoprint
Course Reserves – All required and suggested textbooks for your courses can be accessed through the Courses Reserves guide. We strive to make all your required textbooks available in an electronic format, but there are a few that are print only. Not to worry, we also keep a print copy of required textbooks in our reserve collection, so you can check out a copy for a couple of hours if you need to.
Equipment – The checking out of equipment such as laptops, headphones, and chargers is on hold for now, but be sure to check back in with us.
Complete Anatomy - Complete Anatomy 20 is the world’s most advanced and best-selling 3D anatomy platform, with over 13,000 interactive structures and a living, beating, dissectible human heart in full 3D. This is available to download on your mobile device or desktop. You must use your Mount Sinai email address to set up your account.
Research Discovery Library Catalog – The Library’s catalog, Research Discovery is a simple, one-stop searching platform for journals, articles, books, e-books, digital media, and more in our library’s collection. We also have a curated Special Collection of books on trending and popular topics the you can check out.
Textbooks - Get the textbooks you need! Required and suggested reading for ISMMS Year 1 medical students can be found HERE. Some e-book platforms provide the ability to download PDFs and images of chapters. Just look for the PDF icon for that option. Looking for an annotation app for your notes? Check out our recommendations on our Mobile Apps Guide.
Of course if you have any questions, you can always contact us at refdesk@mssm.edu
Welcome and we look forward to helping you!
Each month Levy Library showcases the achievements of Mount Sinai faculty and researchers by highlighting an article and its altmetrics. Altmetrics are alternative measures of impact that capture non-traditional data like abstract views, article downloads, and social media activity. Our altmetrics data is provided by the PlumX platform.
This month we highlight Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism. This article was written in part by Alexander Kolevzon MD, Silvia De Rubeis PhD, Michael S Breen PhD, Danielle Halpern PsyD, Behrang Mahjani PhD, Sven S. Sandin PhD, and Avraham Reichenberg PhD.
HIGHLIGHTS
102 genes implicated in risk for autism spectrum disorder (ASD genes, FDR ≤ 0.1)
Most are expressed and enriched early in excitatory and inhibitory neuronal lineages
Most affect synapses or regulate other genes; how these roles dovetail is unknown
Some ASD genes alter early development broadly, others appear more specific to ASD
ABSTRACT
We present the largest exome sequencing study of autism spectrum disorder (ASD) to date (n = 35,584 total samples, 11,986 with ASD). Using an enhanced analytical framework to integrate de novo and case-control rare variation, we identify 102 risk genes at a false discovery rate of 0.1 or less. Of these genes, 49 show higher frequencies of disruptive de novo variants in individuals ascertained to have severe neurodevelopmental delay, whereas 53 show higher frequencies in individuals ascertained to have ASD; comparing ASD cases with mutations in these groups reveals phenotypic differences. Expressed early in brain development, most risk genes have roles in regulation of gene expression or neuronal communication (i.e., mutations effect neurodevelopmental and neurophysiological changes), and 13 fall within loci recurrently hit by copy number variants. In cells from the human cortex, expression of risk genes is enriched in excitatory and inhibitory neuronal lineages, consistent with multiple paths to an excitatory-inhibitory imbalance underlying ASD.
View the PlumX article profile